Pre2 Gen2

Drugs may not be sold in the United States until they have been approved by:
A.  The Food and Drug Administration
B.  The National Institute of Drugs             
C.  The American Association of Pharmacists
D.  The Center for Drug Control

According to the Drug Enforcement Agency, which drug class has the highest potential for abuse?
1.  Schedule I
2.  Schedule II                     
3.  Schedule III                    
4.  Schedule IV

When a drug is heavily plasma protein bound, the fraction of the drug that exerts the pharmacological effect is the
A.  free drug
B. protein bound drug
C. both the free and protein bound drug
D. metabolized drug fragments

Most drug metabolism occurs in the
A. liver
B. kidney
C. intestines
D. gall bladder

An important advantage of administering a drug intravenously is that
1.  you can control the duration of action.
2.  there are fewer adverse effects.       
3.  the onset of action is faster than other routes.
4.  first pass metabolism is enhanced.

Which pregnancy category indicates that controlled studies in humans have not shown risk to the mother or fetus?
A.  Category A
B.  Category C
C.  Category D                     
D.  Category X

Which pregnancy category indicates that animal studies and clinical trials show a significant risk to the mother and/or fetus that clearly outweighs any benefit that might be derived?
A.  Category A
B.  Category C
C.  Category D
D.  Category X

The Federal Food, Drug and Cosmetics Act said that drugs must be safe before they can be marketed. This law passed in:
A.  1906
B.  1914
C.  1938
D.  1994

The drug Levoxine was renamed as Levoxyl because:
A.  the patent had expired
B.  of a patent infringment
C.  it had been mistaken as levorphanol
D.  it had been mistaken as Lanoxin

Factors which effect pharmacokinetics or dynamics in the elderly include:
A.  Lower body fat
B.  Better kidney function
C.  Higher serum protein
D.  Drug interactions

After a drug is administered, it must get to the site where it exerts its action. This phase of pharmacokinetics is called
1. Absorption
2. Distribution
3. Metabolism
4. Excretion

When two or more drugs are given together and the result is smaller than you would have seen if the drugs had been given alone, you have a drug interaction known as:
A. summation
B. potentiation
C. synergy
D. antagonism

If a rapid onset of action is important, which route of administration would you choose?
1. Transcutaneous
2. Inhaled
3. Intravenous
4. Oral